Genes
found to increase obesity risk up to sixfold
NEW YORK: Scientists have discovered rare genetic variants that can increase
the risk of obesity by up to six times.
According
to media reports, researchers at the Medical Research Council have identified
genetic variants in two genes that have the greatest influence on obesity risk
ever discovered.
Experts
say that these rare variants discovered in genes (BSN and APBA1) are some of
the first to be discovered to be associated with obesity, with no increase in
risk observed until adulthood. has been.
Study
author Professor Giles Yeo, from the MRC Metabolic Disease Unit, said the
scientists had discovered two genes with variants that had the greatest impact
on obesity risks. However, this variation is not associated with childhood
obesity, but with onset in adulthood.
He said
the findings will provide scientists with new insights into the relationship
between genetics, neurodevelopment and obesity.
The
researchers carried out whole-exome sequencing of the body mass index (BMI) of
more than 500,000 people using data from the UK Biobank and other information
sources for the study.
This
process is a type of genetic sequencing that is used to understand what causes
factors or disease.
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